Prevalence and antimicrobial resistance of bacterial agents isolated from the cases of dental caries.

Dental caries are mainly occur owing to the presence and activity of bacterial agents. The present study was done to assess the prevalence and antibiotic resistance of bacterial strains isolated from the cases of dental caries. Fifty patients with approved dental carries were included in the study. Sampling from the site of dental caries was done using the sterile swab. Swabs were transferred to laboratory and subjected to microbial culture. Species identification of bacteria was done using biochemical test. Bacterial isolates were subjected to disk diffusion to assess their antimicrobial resistance. S. aureus (40%) harboured the highest rate of contamination, while S. oralis (16%) and E. aerogenes (10%) harbored the lowest. S. aureus and S. mutans (6%) harbored the highest distribution amongst the cases of mix infections, while S. aureus and S. oralis (2%) harbnored the lowest. S. aureus strains harbored the highest rate of resistance toward tetracycline (90%), penicillin (75%), ampicillin (75%), amoxicillin (60%), and erythromycin (60%). E. coli strains harbored the highest rate of resistance toward tetracycline (90%), gentamicin (80%), ampicillin (70%), and erythromycin (70%). S. mutans strains harbored the highest rate of resistance toward tetracycline (93.33%), ampicillin (86.66%), penicillin (80%), amoxicillin (80%), and erythromycin (80%). S. oralis strains harbored the highest rate of resistance toward tetracycline (100%), ampicillin (75%), penicillin (62.50%), and amoxicillin (62.50%). E. aerogenes strains harbored the highest rate of resistance toward tetracycline (80%), gentamicin (80%), and ampicillin (80%). S. aureus bacteria isolated from dental caries harbored the highest rate of MDR. Distribution of resistance against more than 3 antimicrobial agents amongst the S. aureus, E. coli, S. mutans, S. oralis, and E. aerogenes bacteria isolated from the cases of dental caries was 90%, 60%, 80%, 62.50%, and 80%, respectively. Application of disk diffuin can help practitioners to reduce the rate of resistance in bacteria responsible for dental caries.

Effects of greenery enhancements for the resilience to heat waves: A comparison of analysis performed through mesoscale (WRF) and microscale (Envi-met) modeling.

Given the large transformation and fast-growing population that the Greater Toronto Area (GTA) is facing, and the increasing impact of climate change in urbanized areas, it is crucial to investigate strategies that could mitigate the effects of heat waves. In this paper, the effects of greenery enhancements are investigated using mesoscale and microscale simulations performed by the Weather Research and Forecasting model and the ENVI-met model, respectively. In particular, two vulnerable areas located in the GTA are investigated. Comparing the results of simulations with measurements show the differences in how mesoscale and microscale models predict the meteorological processes happening within the urban canopy and the local climate. Then, two mitigation scenarios, a moderate green scenario (MGS) and an intensive green scenario (IGS) are assessed considering different increases in the vegetation area. The results of the mesoscale simulations show that by increasing the greenery canopy, the maximum daily air temperature decreases by 1.6 to 2.3 °C, while the relative humidity increases by 10% to 12%. The microscale simulations show that increasing the tree canopy would cool the air temperature by 0.5 °C to 1.4 °C locally. Overall, depending on wind conditions and the arrangement of buildings and existing green areas, the cooling effect is shown to have an impact on up to 250 m downwind from the new green area locations. Finally, this study demonstrates that both mesoscale (WRF) and microscale (ENVI-met) modeling confirm similar results in how greenery enhancements may improve the human thermal comfort in the continental climate of the GTA.

Comparison of skeletal changes related to patients with chronic kidney disease and healthy individuals in digital panoramic radiography.

BACKGROUND: Chronic kidney disease (CKD) is a prevalent condition affecting bone metabolism. Bone changes in CKD patients also known as renal osteodystrophy happen due to disorders in the regulation of water and electrolytes caused by the disease. The aim of this study is to investigate the bone changes of CKD stages 3-5 patients without dialysis using digital panoramic radiography. MATERIALS AND METHODS: In this cross-sectional study, panoramic radiographs were obtained from 30 patients with CKD stages 3-5 and 30 age and gender matched healthy individuals. The mean values of quantitative parameters such as mental index (MI), panoramic mandibular index (PMI), and antegonial index (AI) were measured and qualitative parameters such as mandibular cortical index (MCI) and trabecular bone pattern (TP) were recorded based on Kelemetti and Lindh calcifications, respectively. Statistical analysis was performed using t-test, Chi-square, and Mann-Whitney test (α = 0.05). RESULTS: The mean values of MI, PMI, and AI in the two groups were not statistically significant (P > 0.05). MCI and TP were significantly different between the two groups. MCI showed more defects in mandibular cortex of CKD patients (6.7% of patients vs. 0% of control group were C3, P = 0.038), and TP showed more porosity in mandibular bone of CKD patients (10% of patients vs. 0% of control group were sparse, P = 0.001). CONCLUSION: The amount of MI, PMI, and AI were not related to CKD. While MCI and TP were significant parameters that showed mandibular cortical situation and trabecular bone pattern, they assess osteoporosis level in a more reliable manner in CKD stages 3-5 patients without dialysis.